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INDUSTRY SPONSORED RESEARCH

Ongoing (As at 29 Nov 2022)
No.
Research Title
Investigator
Status
1. AEGIS II – A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subject with Acute Coronary Syndrome

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Dato’ Sri Dr. Haji Azhari Rosman Enrollment
2. APPIRED III – Preventing Oxidative Stress Induced Ischemic Injury and Systemic Inflammation Complications During and After Invasive Cardiac Surgery with Alkaline Phosphatase

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Dr. Pau Kiew Kong Enrollment
3. ABILITY DIABETES – Randomized Comparison of Abluminus DES+ Sirolimus-Eluting Stents versus Everolimus-Eluting Stents in Coronary Artery Disease Patients with Diebetes Mellitus Global.

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Dato’ Dr. Amin Ariff Nuruddin Enrollment
4. COMBINE-INTERVENE – COMBINEd Ischemia and Vulnerable Plaque Percutaneous INTERVENtion to Reduce Cardiovascular Events.

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Dato’ Dr. Amin Ariff Nuruddin Enrollment
5. LEADR – Lead Evaluation for Defibrillation and Reliability

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Dr. Surinder Kaur Khelae Enrollment
6. CTO Registry using the HYBRID CTO ALGORITHM at IJN. (Device : Crossboss & Stingray)

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Datuk Dr. Shaiful Azmi Yahaya Enrollment
7. FINEARTS – A multicentre, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of finerenone on morbidity and mortality in participants with heart failure(NYHA II-IV) and EF ≥40%

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Dr. Teoh Chee Kiang Enrollment
8. DEDICATE REGISTRY – A Post Market Registry of Abluminum® Sirolimus Eluting Coronary Stent System for Percutaneous Intervention in Patients with Diabetic Mellitus

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Dato’ Sri Dr. Haji Azhari Rosman Enrollment
9. GSR DEFINE – Global SYMPLICITY Registry (GSR) Denervation Findings in Real World (DEFINE) is referred to as the GSR DEFINE study

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Dato’ Dr. Amin Ariff Nuruddin Enrollment
10. FIM-IBS – A Prospective, Non-randomized, Open lable, Non-comparative, First-in-Man Study to Evaluate the Feasibility and Safety of Sirolimus-eluting Iron Bioresorbable Coronary Scaffold System

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Datuk Dr. Shaiful Azmi Yahaya Enrollment
11. ZEUS – Effects of ziltivekimab versus placebo on cardiovascular outcomes in participants with established atherosclerotic cardiovascular disease, chronic kidney disease and systemic inflammation

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Dato’ Sri Dr. Haji Azhari Rosman Enrollment
12. MID-Q Response

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Datuk Dr. Azlan Hussin Enrollment
13. NEOS-APAC – Asian Pacific post-market clinical follow-up study in patients with acute or chronic aortic dissection or aortic aneurysm treated with E-vita OPEN NEO

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Mr. Paneer Selvam Enrollment
14. RESTORE – A Prospective, Multicenter, Single-Arm, Open-Label, Phase 4 Study of the Effects of Selexipag on Right Ventricular Remodeling in Pulmonary Arterial Hypertension Assessed by Cardiac Magnetic Resonance Imaging

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Dr. Geetha A/P Kandavello @ Kandhavel Enrollment
15. TOMORROW – A Multicenter, Open-label, Randomized, Event-driven Study to Assess Efficacy, Safety and Pharmacokinetics of Macitentan Versus Standard of Care in Children with Pulmonary Arterial Hypertension

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Dr. Geetha A/P Kandavello @ Kandhavel Enrollment
16. VFAHF STUDY – Ventricle from Atrium Heart Failure Clinical Study (VFAHF)

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Datuk Dr. Azlan Hussin Enrollment
17. SALTO – A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Parallel-Group, Event-Driven, Group-Sequential Study with Open-Label Extension Period to Assess the Efficacy and Safety of Selexipag as Add-On Treatment to Standard of Care in Children Aged ≥2 to <18 years with Pulmonary Arterial Hypertension

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Dr. Geetha A/P Kandavello @ Kandhavel Enrollment
18. SCORE REGISTRY – Sequent® SCB ‘’All Comers’’ Post Market Clinical Follow up (PMCF)

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Dato’ Dr. Amin Ariff Nuruddin Enrollment
19. STRIDE – Effects of semaglutide on functional capacity in patients withtype 2 diabetes and peripheral arterial disease

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Datuk Dr. Shaiful Azmi Yahaya Enrollment
20. PRIME-FFR – Prognostic impact of lesion-specific hemodynamic index and disease characteristics in patients with coronary artery disease assessed by fractional flow reserve

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Datuk Dr. Azlan Hussin Enrollment
Ongoing (As at 29 Nov 2022)
No.
Research Title Investigator
Status
1. BIOLUX P-III REGISTRY – BIOTRONIK-A Prospective, International, Multi-Centre, Post-Market All-Comers Registry To Assess The Clinical Performance Of The Passeo-18 Lux Paclitaxel Releasing Balloon Catheter In Infraguinal Arteries -III

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Datuk Dr. Shaiful Azmi Yahaya Follow Up
2. Meres-1 Extend – A Prospective, Multinational, Multicenter, Single Arm, Open Label, Pilot Clinical Study Of Meres100 Sirolimus Eluting Bioresorbable Vascular Scaffold System In The Treatment Of De-Novo Native Coronary Artery Lesions

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Dato’ Dr. Amin Ariff Nuruddin Follow Up
3. ABSORB BVS – Comparative Study In Real World Use Of The ABSORB Bioresorbable Vascular Scaffold In De Novo Coronary Artery Disease Among Diabetes And Non-Diabetes Patient In Institut Jantung Negara, Malaysia: A Prospective Post-Marketing Single-Center Registry

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Datuk Dr. Shaiful Azmi Yahaya Follow Up
4. CONSEQUENT ALL COMERS – Clinical PMCF on Peripheral Arteries treated with SeQuent® Please OTW Paclitaxel Coated Balloon Catheter in an All Comer Patient Population

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Datuk Dr. Shaiful Azmi Yahaya Follow Up
5. ISCHEMIA – International Study of Comparative Health Effectiveness With Medical and Invasive Approaches

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Datuk Dr. Ahmad Khairuddin Mohamed Yusof Follow Up
6. The EASTBOURNE Registry – The All-comers Sirolimus-coated balloon European registry

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Dato’ Dr. Amin Ariff Nuruddin Follow Up
7. SCB DE-NOVO STUDY – Treatment of coronary de-novo stenosis by a sirolimus coated balloon or a paclitaxel coated balloon catheter

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Dato’ Dr. Amin Ariff Nuruddin Follow Up
8. BIOSOLVE-IV REGISTRY – Safety And Performance In De Novo Lesion Of Native Coronary Arteries With Magmaris – Registry Data

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Dato’ Dr. Amin Ariff Nuruddin Follow Up
9. MYHF – Malaysian National Heart Failure Registry

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Dato’ Dr. Azmee Bin Mohd Ghazi Follow Up
10. SELECT STUDY – Semaglutide effects on cardiovascular outcomes in people with overweight or obesity

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Dato’ Sri Dr. Haji Azhari Rosman Follow Up
11. BGSAMIRP – Blood-based Genomic Signatures in Acute Myocardial Infarction Risk Prediction

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Dato’ Dr. Amin Ariff Nuruddin Follow Up
12. CAAN-AF – Cardiac Resynchronization therapy (CRT) And AV Node ablation in Atrial Fibrillation

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Datuk Dr. Azlan Hussin Follow Up
13. PROTECT-ICD Trial – Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction

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Dr. Geetha A/P Kandavello @ Kandhavel Follow Up
14. CRYO AF GLOBAL REGISTRY

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Dr. Surinder Kaur Khelae Follow Up
15. A DUE – Prospective, multi-center, double-blind, randomized, active-controlled, triple-dummy, parallel-group, group-sequential, adaptive Phase 3 clinical study to compare the efficacy and safety of macitentan and tadalafil monotherapies with the corresponding fixed dose combination in subjects with pulmonary arterial hypertension (PAH), followed by an open-label treatment period with macitentan and tadalafil fixed dose combination therapy

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Dr. Geetha A/P Kandavello @ Kandhavel Follow Up
16. BIOFLOW-DAPT – BIOTRONIK – A Prospective, Randomized, Multi-center Study to Assess the SaFety of the Orsiro Mission Stent compared to the ResoLute Onyx Stent in Subjects at High Risk for Bleeding in combination With 1-month Dual Antiplatelet Therapy (DAPT)

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Datuk Dr. Shaiful Azmi Yahaya Follow Up
17. MICRA AV – Product Surveillance Registry (PSR)

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Datuk Dr. Azlan Hussin Follow Up
Completed (As at 29 Nov 2022)
No.
Research Title Investigator
Status
Research are in progress..
Research are in progress..